From Commensal to Consumer: Toxins, Diseases, and Detection Methods.

Angela T Nguyen, Sandra M Tallent

Journal: Journal of AOAC International 2018;101(4):1127-1134

PMID: 29216934

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Abstract

Staphylococcus aureus is a Gram-positive bacterium capable of causing a wide array of infections. Generally a commensal organism, S. aureus encodes several virulence mechanisms that contribute to disease progression. This review highlights toxins as a secreted virulence factor by S. aureus, the diseases that manifest as a result, and the methods used to detect them. In particular, the advantages and limitations of current toxin detection methods are discussed.

Address: U.S. Food and Drug Administration, Center for Food Safety and Applied Nutrition, 5001 Campus Dr, College Park, MD 20740, USA.

DOI: 10.5740/jaoacint.17-0366

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MeSH Terms: Bacterial Toxins, Disease Reservoirs, Humans, Immunoassay, Staphylococcal Food Poisoning, Staphylococcal Infections, Staphylococcus aureus, Toxins, Biological, Virulence Factors