PET imaging in glioma: techniques and current evidence.

Nina M Mansoor, Stefanie Thust, Vincenzo Militano, Francesco Fraioli

Journal: Nuclear medicine communications 2018;39(12):1064-1080

PMID: 30303860

Abstract

PET holds potential to provide additional information about tumour metabolic processes, which could aid brain tumour differential diagnosis, grading, molecular subtyping and/or the distinction of therapy effects from disease recurrence. This review discusses PET techniques currently in use for untreated and treated glioma characterization and aims to critically assess the evidence for different tracers ([F]Fluorodeoxyglucose, choline and amino acid tracers) in this context.

Address: Department of Brain Rehabilitation and Repair, UCL Institute of Neurology.; Lysholm Department of Neuroradiology, National Hospital for Neurology and Neurosurgery.; Institute of Nuclear Medicine, University College London Hospital, London, UK.

DOI: 10.1097/MNM.0000000000000914

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MeSH Terms: Glioma, Humans, Neoplasm Grading, Positron-Emission Tomography