Yupeng Pan, Esther van der Knaap, Tea Meulia, Antonio J Monforte, Johan Willemsen, Herman van Eck, Shelley H Jansky, Yiqun Weng, C Robin Buell, Dennis Halterman, Courtney P Leisner, Shan Wu, Aurora Díaz, M J Gonzalo, Nathan K Taitano, Eudald Illa-Berenguer, Manohar Chakrabarti, Hyun Jung Kim, Gustavo R Rodríguez, Neda Keyhaninejad, Biyao Zhang
Journal: Nature communications 2019;9(1):4734
PMID: 30413711
Shapes of edible plant organs vary dramatically among and within crop plants. To explain and ultimately employ this variation towards crop improvement, we determined the genetic, molecular and cellular bases of fruit shape diversity in tomato. Through positional cloning, protein interaction studies, and genome editing, we report that OVATE Family Proteins and TONNEAU1 Recruiting Motif proteins regulate cell division patterns in ovary development to alter final fruit shape. The physical interactions between the members of these two families are necessary for dynamic relocalization of the protein complexes to different cellular compartments when expressed in tobacco leaf cells. Together with data from other domesticated crops and model plant species, the protein interaction studies provide possible mechanistic insights into the regulation of morphological variation in plants and a framework that may apply to organ growth in all plant species.
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