Neuroscience: Modeling the Brain on Acid.

Johan van der Meer, Michael Breakspear

Journal: Current biology : CB 2019;28(19):R1157-R1160

PMID: 30300604

Free Full Text on Elsevier Science View on PubMed

Abstract

A receptor map of serotonin distribution is integrated into a model of the dynamic activity of the brain under the effects of LSD. The approach opens new avenues to understand experimental manipulations of healthy brain activity and offers a novel drug-discovery platform.

Address: QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia; Centre of Excellence for Integrative Brain Function, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia; Metro North Mental Health Service, Brisbane, Queensland, Australia. Electronic address: [email protected].

DOI: 10.1016/j.cub.2018.08.008

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MeSH Terms: Brain, Lysergic Acid Diethylamide, Neuroimaging, Receptors, Serotonin, Serotonin