Intravenous Iron Therapy in Heart Failure.

Natasha L Altman, Amit Patel

Journal: Heart failure clinics 2018;14(4):537-543

PMID: 30266362

Full Text on Elsevier Science View on PubMed

Abstract

Iron deficiency anemia is both a comorbid condition and an indicator of poor prognosis in heart failure. The mechanisms by which this occurs are multiple and complex. Recent robust randomized clinical trials have shown significant improvements in quality of life and rates of hospitalization with intravenous repletion of iron. In this article, we review the mechanisms by which iron deficiency impacts heart failure and the evidence behind repletion. There remains a good deal to learn about long-term effects of intravenous iron repletion, and clinical trials are ongoing in this regard.

Address: Section of Advanced Heart Failure and Transplant, Division of Cardiology, Department of Medicine, University of Colorado Denver, 12631 East 17th Avenue, Aurora, CO 80045, USA. Electronic address: [email protected].; Advanced Heart Failure and Cardiac Transplantation, St. Vincent Medical Group, 8333 Naab Road, Suite 400, Indianapolis, IN 46260, USA.

DOI: 10.1016/j.hfc.2018.06.003

Link outs

Free resources

Medical:

https://medlineplus.gov/heartfailure.html

Other Literature Sources:

https://scite.ai/reports/30266362

Subscription / membership required

Full Text Sources:

MeSH Terms: Administration, Intravenous, Anemia, Iron-Deficiency, Heart Failure, Humans, Iron