A detailed guide to lipid therapy in intestinal failure.

Kathleen M Gura, McGreggor Crowley

Journal: Seminars in pediatric surgery 2018;27(4):242-255

PMID: 30342599

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Abstract

Intravenous lipid emulsions are an integral part of nutrition therapy in the intestinal failure patient. In addition to being a concentrated source of non-protein calories, they provide the essential fatty acids necessary for growth and development. Depending upon the oil source used in these products, complications such as intestinal failure associated liver disease (IFALD) can occur. This review will discuss the risks and benefits associated with these products, especially as they relate to the pediatric intestinal failure patient.

Address: Clinical Research, Department of Pharmacy, Clinical Pharmacist GI/Nutrition, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA. Electronic address: [email protected].; Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA. Electronic address: [email protected].

DOI: 10.1053/j.sempedsurg.2018.07.003

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MeSH Terms: Fat Emulsions, Intravenous, Humans, Intestinal Diseases, Liver Diseases, Treatment Outcome