The influence of standardized dry ivy leaf extract on the proportion of nasal secretion after post-septoplasty nasal packing removal.

Slobodan Savović, Milica Paut Kusturica, Vladimir Kljajić, Maja Buljčik Čupić, Ljiljana Jovančević, Vedrana Pavlović, Aleksandar Rašković

Journal: Brazilian journal of otorhinolaryngology 2019;85(6):685-689

PMID: 30017873

Abstract

INTRODUCTION

After post-septoplasty nasal packing removal, a certain proportion of nasal secretion occurs, leading to local and sometimes systemic infections.

OBJECTIVE

The aim was to determine if standardized dry ivy leaf extract application after nasal packing removal influences the reduction of nasal secretion and diminish the occurrence of local infections.

METHODS

The study included 70 post-septoplasty patients (divided into two equal groups) whose nasal packing was removed on the third day after the procedure. Group I was treated with standardized dry ivy leaf extract syrup along with regular nasal irrigation for the five days after the nasal packing removal whereas the Group II had only nasal lavage. On the sixth day after nasal packing removal, the quantity of nasal secretion was determined using a visual analog scale and nasal endoscopic examination.

RESULTS

The group treated with standardized dry ivy leaf extract syrup had significantly lesser nasal secretion both by subjective patients' assessment (p<0.001) and by nasal endoscopic examination (p=0.003). The post-surgical follow up examination on the sixth day after nasal packing removal showed no development of local infection in the Group I, while in the Group II a local infection was evident in five patients (14.29%) and antibiotic therapy was required.

CONCLUSION

The use of the standardized dry ivy leaf extract after nasal packing removal significantly lowers the proportion of nasal secretion.

Copyright © 2018 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. All rights reserved.

Address: University of Novi Sad, Faculty of Medicine, Clinical Centre of Vojvodina, Ear, Nose and Throat Clinic, Novi Sad, Serbia.; University of Novi Sad, Faculty of Medicine Novi Sad, Department of Pharmacology Toxicology and Clinical Pharmacology, Novi Sad, Serbia. Electronic address: [email protected].; University of Belgrade, Faculty of Medicine, Belgrade, Serbia.; University of Novi Sad, Faculty of Medicine Novi Sad, Department of Pharmacology Toxicology and Clinical Pharmacology, Novi Sad, Serbia.
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