Proximal-type epithelioid sarcoma of the oral cavity: a case report and literature review.

Yutong Liu, Bincan Sun, Yaocheng Yang, Liang Zhong, Xifan He, Mengxue Wang, Kai Wang, Lin Chen

Journal: Oral surgery, oral medicine, oral pathology and oral radiology 2019;126(5):e258-e263

PMID: 30087080

Full Text on Elsevier Science View on PubMed

Abstract

Proximal-type epithelioid sarcoma (PES) is an exceedingly rare malignant tumor of soft tissue; PES within the oral cavity is even rarer. Pathologic examination is the primary diagnostic modality, and surgical treatment is recommended as the preferred method for the treatment of PES. Currently, there is a paucity of literature that systematically reports on PES in the oral cavity. Here, we describe a 42-year-old man with PES in the oral cavity, which showed positivity for vimentin, cytokeratin, CD31, S-100 but did not express BCL-2, HMB-45, or desmin. We performed a wide excision and neck dissection, and then used the free anterolateral thigh flap to reconstruct the defect in the soft tissue. Furthermore, we review the current literature with regard to diagnosis and treatment of PES.

Address: Department of Oral and Maxillofacial Surgery, The Second Xiangya Hospital, Central South University, Changsha 410011, P. R. China.; Department of Oral and Maxillofacial Surgery, The Second Xiangya Hospital, Central South University, Changsha 410011, P. R. China. Electronic address: [email protected].; Department of Oral and Maxillofacial Surgery, The Second Xiangya Hospital, Central South University, Changsha 410011, P. R. China. Electronic address: [email protected].

DOI: 10.1016/j.oooo.2018.05.049

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MeSH Terms: Adult, Diagnosis, Differential, Diagnostic Imaging, Free Tissue Flaps, Humans, Male, Mouth Neoplasms, Neck Dissection, Sarcoma, Soft Tissue Neoplasms, Thigh