Metabolic support challenges with obesity during critical illness.

Roland N Dickerson

Journal: Nutrition (Burbank, Los Angeles County, Calif.) 2020;57():24-31

PMID: 30153576

Full Text on Elsevier Science View on PubMed

Abstract

Adiposity-based chronic disease, critical illness, and nutrition therapy increase the risk for overfeeding and worsened nutritional and clinical outcomes. Hypocaloric, high-protein nutrition therapy provides critically ill obese patients the opportunity to achieve net protein anabolism with a reduced risk for overfeeding-related complications. The intent of this review is to discuss the impact of obesity on clinical outcomes, describe the consequences of obesity that increase complications associated with nutrition therapy, provide the framework to develop a hypocaloric, high-protein regimen, review the scientific evidence to support this mode of therapy, and discuss its limitations. Practical suggestions for patient monitoring are also provided.

Address: College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee. Electronic address: [email protected].

DOI: 10.1016/j.nut.2018.05.008

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MeSH Terms: Critical Illness, Humans, Nutritional Requirements, Nutritional Support, Obesity