The effect on the hemodynamic stability of varying calcium chloride administration during protamine infusion in pediatric open-heart patients.

V Muangmingsuk, T F Tremback, S Muangmingsuk, D A Roberson, N E Cipparrone

Journal: Anesthesia and analgesia 2001;93(1):92-5, TOC

PMID: 11429346

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Abstract

We conducted a randomized study in 147 pediatric patients undergoing cardiopulmonary bypass to determine when there are any differences in hemodynamic effects if CaCl(2) 20 mg/kg and protamine 5mg/kg are mixed together and infused over 10 min versus administering half of the calcium dose (10 mg/kg) as a bolus followed by a 10-min infusion of protamine 5 mg/kg and CaCl(2) 10mg/kg.

Address: Department of Anesthesia, The Heart Institute for Children, Advocate Christ Hospital and Medical Center, Oak Lawn, IL 60453, USA.

DOI: 10.1097/00000539-200107000-00020

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MeSH Terms: Adolescent, Anesthesia, General, Body Temperature, Calcium Chloride, Cardiac Surgical Procedures, Child, Child, Preschool, Female, Heart Defects, Congenital, Hemodynamics, Heparin Antagonists, Humans, Infant, Infant, Newborn, Infusions, Intravenous, Male, Oxygen, Protamines, Ventricular Function, Left