Fractional flow reserve-CT assessment of coronary stenosis.

Edmund K Kerut, Michael Turner

Journal: Echocardiography (Mount Kisco, N.Y.) 2018;35(5):730-732

PMID: 29569282

Abstract

Coronary computed tomography angiography (CCTA) has been an established noninvasive method for detection of coronary artery disease (CAD). Although CCTA has had a high sensitivity and negative predictive value for CAD detection, specificity for obstructive CAD has been relatively low, partly due to coronary calcium, imaging artifacts, and other factors leading to an overestimation of stenosis severity. A relatively new noninvasive method of calculation of fractional flow reserve (FFR) using CCTA (FFR ) data has been developed. This noninvasive method yields similar results to invasive FFR measurement, improving specificity for noninvasively detecting lesion-specific ischemia thus helping guide revascularization.

Address: Division of Cardiovascular Diseases, Department of Medicine, University of Mississippi School of Medicine, Jackson, MS, USA.; Heart Clinic of Louisiana, Marrero, LA, USA.; Cardiovascular Specialists of Southwest Louisiana, Lake Charles, LA, USA.

DOI: 10.1111/echo.13867

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https://doi.org/10.1111/echo.13867

MeSH Terms: Computed Tomography Angiography, Coronary Angiography, Coronary Stenosis, Coronary Vessels, Fractional Flow Reserve, Myocardial, Humans, ROC Curve, Severity of Illness Index