Review shows that implementing a nationwide protocol for congenital diaphragmatic hernia was a key factor in reducing mortality and morbidity.

L Storme, J Boubnova, S Mur, L Pognon, D Sharma, E Aubry, R Sfeir, P Vaast, T Rakza, A Benachi

Journal: Acta paediatrica (Oslo, Norway : 1992) 2019;107(7):1131-1139

PMID: 29193315

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Abstract

UNLABELLED

The French Rare Disease Reference Center for congenital diaphragmatic hernia (CDH) was created in 2008, to implement a national protocol for foetuses and children with this serious condition. Neonatal mortality from CDH is 30-40%, mainly due to pulmonary hypoplasia and persistent pulmonary hypertension, and half of those who live have high respiratory, nutritional and digestive morbidity. CDH management requires long-term and specialised multidisciplinary care. It has been well established that a standardised management protocol improves the prognosis of children with CDH.

CONCLUSION

Organising health care and implementing a nationwide French protocol were key factors for reducing mortality and morbidity from CDH.

Address: Lille coordinating center, Jeanne de Flandre Hospital, Lille Regional University Hospital, Lille, France.; Marseille coordinating center, AP-HM, La Timone Hospital, Marseille, France.; Paris coordinating center, AP-HP, Antoine Béclère Hospital, Clamart, France.

DOI: 10.1111/apa.14169

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MeSH Terms: Clinical Protocols, France, Hernias, Diaphragmatic, Congenital, Humans, Perinatal Care, Prenatal Care, Respiratory Insufficiency