Normal saline for intravenous fluid therapy in critically ill patients.

Fei-Hu Zhou, Chao Liu, Zhi Mao, Peng-Lin Ma

Journal: Chinese journal of traumatology = Zhonghua chuang shang za zhi 2018;21(1):11-15

PMID: 29429774

Free Full Text on Elsevier Science View on PubMed

Abstract

The efficacy and safety of normal saline (NS) for fluid therapy in critically ill patients remain controversy. In this review, we summarized the evidence of randomized controlled trials (RCTs) which compared NS with other solutions in critically ill patients. The results showed that when compared with 6% hydroxyethyl starch (HES), NS may reduce the onset of acute kidney injury (AKI). However, there is no significant different in mortality and incidence of AKI when compared with 10% HES, albumin and buffered crystalloid solution. Therefore, it is important to prescribe intravenous fluid for patients according to their individual condition.

Address: Department of Critical Care Medicine, Chinese People's Liberation Army General Hospital, Beijing 100853, China.; Department of Critical Care Medicine, 309th Hospital of Chinese People's Liberation Army, Beijing 100091, China. Electronic address: [email protected].

DOI: 10.1016/j.cjtee.2017.04.012

Link outs

Free resources

Full Text Sources:

Other Literature Sources:

https://scite.ai/reports/29429774

Miscellaneous:

https://assays.cancer.gov/CPTAC-76

MeSH Terms: Albumins, Critical Illness, Crystalloid Solutions, Fluid Therapy, Humans, Hydroxyethyl Starch Derivatives, Isotonic Solutions, Sodium Chloride