Self-assembled vertically aligned Au nanorod arrays for surface-enhanced Raman scattering (SERS) detection of Cannabinol.

Sarah Milliken, Jeff Fraser, Shawn Poirier, John Hulse, Li-Lin Tay

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 2018;196():222-228

PMID: 29453097

Full Text on Elsevier Science View on PubMed

Abstract

Self-assembled multi-layered vertically aligned gold nanorod (AuNR) arrays have been fabricated by a simple preparation process that requires a balance between the particle concentration and the ionic strength of the solvent. An experimentally determined critical AuNR concentration of 2.0nM and 50mM NaCl produces well-ordered vertically aligned hexagonally close-packed AuNR arrays. We demonstrate surface treatment via UV Ozone cleaning of such samples to allow introduction of analyte molecules (benzenethiol and cannabinol) for effective surface enhanced Raman scattering detection. This is the first demonstration of the SERS analysis of cannabinol. This approach demonstrates a cost-effective, high-yield and simple fabrication route to SERS sensors with application in the screening for the cannabinoids.

Address: National Research Council Canada, Measurement Science and Standards, Ottawa, ON K1A0R6, Canada.; National Research Council Canada, Measurement Science and Standards, Ottawa, ON K1A0R6, Canada. Electronic address: [email protected].

DOI: 10.1016/j.saa.2018.01.030

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MeSH Terms: Cannabinol, Gold, Nanotubes, Phenols, Sodium Chloride, Spectrum Analysis, Raman, Sulfhydryl Compounds