Diabetic macular edema grading in retinal images using vector quantization and semi-supervised learning.

Fulong Ren, Peng Cao, Dazhe Zhao, Chao Wan

Journal: Technology and health care : official journal of the European Society for Engineering and Medicine 2018;26(S1):389-397

PMID: 29689762

Abstract

BACKGROUND

Diabetic macular edema (DME) is one of the severe complication of diabetic retinopathy causing severe vision loss and leads to blindness in severe cases if left untreated.

OBJECTIVE

To grade the severity of DME in retinal images.

METHODS

Firstly, the macular is localized using its anatomical features and the information of the macula location with respect to the optic disc. Secondly, a novel method for the exudates detection is proposed. The possible exudate regions are segmented using vector quantization technique and formulated using a set of feature vectors. A semi-supervised learning with graph based classifier is employed to identify the true exudates. Thirdly, the disease severity is graded into different stages based on the location of exudates and the macula coordinates.

RESULTS

The results are obtained with the mean value of 0.975 and 0.942 for accuracy and F1-scrore, respectively.

CONCLUSION

The present work contributes to macula localization, exudate candidate identification with vector quantization and exudate candidate classification with semi-supervised learning. The proposed method and the state-of-the-art approaches are compared in terms of performance, and experimental results show the proposed system overcomes the challenge of the DME grading and demonstrate a promising effectiveness.

Address: School of Computer Science and Engineering, Northeastern University, Shenyang, Liaoning, China.; Key Laboratory of Medical Image Computing of Ministry of Education, Northeastern University, Shenyang, Liaoning, China.; Department of Ophthalmology, The First Hospital of China Medical University, Shenyang, Liaoning, China.
Bant logo

© Copyright 2026, Nutrition Evidence

NED wishes to thank the following organisations for their support:

We use cookies to improve your experience and analyze site traffic with Google Analytics. By continuing to use our site, you agree to our use of cookies. Learn more.