Muscular Atrophy in Cardiovascular Disease.

Rodrigo Della Méa Plentz, Isadora Rebolho Sisto, Melina Hauck

Journal: Advances in experimental medicine and biology 2019;1088():369-391

PMID: 30390261

Abstract

Currently, the number of chronic diseases has increased due to increasing in life expectancy of population. Among them, cardiovascular diseases (CVD) are the most prevalent and responsible for the high mortality and morbidity rates. Patients with CVD have metabolic, hemodynamic, and musculoskeletal changes. There is a debate regarding the correct term for musculoskeletal changes that affect this group of patients; therefore, we found in literature myopia, muscular atrophy, cardiac cachexia, and sarcopenia. However, although there is no standardization in relation to correct term, these musculoskeletal consequences directly affect the quality of life and are associated with a poor prognosis. In this way, the importance of prevention of muscular atrophy, but also of treatment for those patients with progressive muscle decline, is proven. We also emphasize the importance of a multi-professional team, because therapeutic strategies are needed that are capable of delaying the onset or minimizing the consequences of skeletal muscle loss, from pharmacological management and nutrition to physical exercise.

Address: Graduate Program in Rehabilitation, Federal University of Health Sciences of Porto Alegre, Porto Alegre, Brazil.; Graduate Program in Health Science, Federal University of Health Sciences of Porto Alegre, Porto Alegre, Brazil.; Graduate Program in Health Sciences, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Rio Grande do Sul, Brazil. [email protected].; Graduate Program in Rehabilitation Sciences, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Rio Grande do Sul, Brazil. [email protected].; Department of Physical Therapy, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Rio Grande do Sul, Brazil. [email protected].

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