X-linked Choroideremia.

Stephen H Tsang, Tarun Sharma

Journal: Advances in experimental medicine and biology 2019;1085():37-42

PMID: 30578482

Abstract

Choroideremia (CHM) is the most common X-linked hereditary choroidal dystrophy, characterized by progressive degeneration of the choriocapillaris, retinal pigment epithelium (RPE), and retina. Its prevalence is about 1 in 50,000-100,000 people.

Address: Jonas Children's Vision Care, Bernard & Shirlee Brown Glaucoma Laboratory, Columbia Stem Cell Initiative-Departments of Ophthalmology, Biomedical Engineering, Pathology & Cell Biology, Institute of Human Nutrition, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Department of Ophthalmology, Columbia University, Edward S. Harkness Eye Institute, NewYork-Presbyterian Hospital, New York, NY, USA.; Department of Ophthalmology, Columbia University, Edward S. Harkness Eye Institute, NewYork-Presbyterian Hospital, New York, NY, USA. [email protected].

DOI: 10.1007/978-3-319-95046-4_9

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https://dx.doi.org/10.1007/978-3-319-95046-4_9

MeSH Terms: Choroideremia, Genetic Diseases, X-Linked, Humans