Extracellular Matrix: Alport Syndrome.

Stephen H Tsang, Tarun Sharma

Journal: Advances in experimental medicine and biology 2019;1085():197-198

PMID: 30578514

Abstract

Patients present with X-linked inheritance; Alport syndrome occurs in approximately 1 in 50,000 newborns. The systemic features include progressive interstitial nephritis, renal failure by the fifth decade, and neurosensory deafness.

Address: Jonas Children's Vision Care, Bernard & Shirlee Brown Glaucoma Laboratory, Columbia Stem Cell Initiative-Departments of Ophthalmology, Biomedical Engineering, Pathology & Cell Biology, Institute of Human Nutrition, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Department of Ophthalmology, Columbia University, Edward S. Harkness Eye Institute, NewYork-Presbyterian Hospital, New York, NY, USA.; Department of Ophthalmology, Columbia University, Edward S. Harkness Eye Institute, NewYork-Presbyterian Hospital, New York, NY, USA. [email protected].

DOI: 10.1007/978-3-319-95046-4_41

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https://dx.doi.org/10.1007/978-3-319-95046-4_41

MeSH Terms: Extracellular Matrix, Genetic Diseases, X-Linked, Humans, Infant, Newborn, Nephritis, Hereditary