Iodine-125 seed implantation for synchronous pancreatic metastases from hepatocellular carcinoma: A case report and literature review.

Junjie Xiong, Selina Kwong Chian, Jiao Li, Xubao Liu

Journal: Medicine 2017;96(46):e8726

PMID: 29145315

Abstract

RATIONALE

The image-guided iodine-125 seed implantation has been widely used for a variety of tumors, including prostatic cancer, pulmonary cancer, hepatocellular carcinoma and pancreatic cancer. However, the clinical value of iodine-125 seed implantation for the treatment of pancreatic metastasis from hepatocellular carcinoma has not been reported. We presented the first case with ultrasound-guided iodine-125 seed implantation for this disease.

PATIENT CONCERNS

We presented the case of a 48-year-old man patient with primary hepatocellular carcinoma and pancreatic metastasis who was managed with ultrasound-guided iodine-125 seeds implantation.

DIAGNOSES

She was diagnosed with synchronous pancreatic metastases from hepatocellular carcinoma.

INTERVENTIONS

Puncture biopsy and ultrasound-guided iodine-125 seeds implantation.

OUTCOMES

The hepatic and pancreatic tumors were obviously reduced after 15 months. Moreover, the liver function test was mildly abnormal in glutamic-oxalacetic transaminase and glutamic-pyruvic transaminase.

LESSONS

The image-guided iodine-125 seeds implantation was an important therapeutic approache to unresectable hepatocellular carcinoma with pancreatic metastasis. However, more related cases should be reported for further evaluating the value of the way.

Address: aDepartment of Pancreatic Surgery bWest China School of Medicine cDepartment of Emergency, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
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