The role of plant panallergens in sensitization to natural rubber latex.

G Salcedo, A Diaz-Perales, R Sanchez-Monge

Journal: Current opinion in allergy and clinical immunology 2002;1(2):177-83

PMID: 11964687

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Abstract

Latex allergy represents an increasing occupational problem, mainly among healthcare workers. An association between latex allergy and hypersensitivity to some plant foods, particularly fruits (the latex-fruit syndrome), has been established. Class I chitinases with an N-terminal hevein-like domain from avocado, chestnut, banana and other foods, and latex hevein seem to be the allergens responsible for the cross-reactions involved in the latex-fruit syndrome. The potential role of other latex allergens, such as profilin, Hev b 5, Hev b 7 and beta-1,3-glucanases, in the co-sensitization to latex and plant foods is also discussed.

Address: Unidad de Bioquímica, Departamento de Biotecnología, E.T.S. Ingenieros Agrónomos, Madrid, Spain.

DOI: 10.1097/01.all.0000011004.49250.bc

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MeSH Terms: Allergens, Amino Acid Sequence, Chitinases, Cross Reactions, Ethylenes, Food Hypersensitivity, Humans, Latex, Latex Hypersensitivity, Molecular Sequence Data, Plants