A randomized, comparative pilot trial of family-based interpersonal psychotherapy for reducing psychosocial symptoms, disordered-eating, and excess weight gain in at-risk preadolescents with loss-of-control-eating.

Nichole R Kelly, Jack A Yanovski, Susan Z Yanovski, Denise E Wilfley, Laura J Dietz, Sheila M Brady, Omni Cassidy, Natasha L Burke, Natasha A Schvey, Lauren B Shomaker, Lisa M Ranzenhofer, Jennifer L Bakalar, Shannon E Marwitz, Cara H Olsen, Rim D Mehari, Camden E Matherne, Marian Tanofsky-Kraff

Journal: The International journal of eating disorders 2018;50(9):1084-1094

PMID: 28714097

Abstract

OBJECTIVE

Preadolescent loss-of-control-eating (LOC-eating) is a risk factor for excess weight gain and binge-eating-disorder. We evaluated feasibility and acceptability of a preventive family-based interpersonal psychotherapy (FB-IPT) program. FB-IPT was compared to family-based health education (FB-HE) to evaluate changes in children's psychosocial functioning, LOC-eating, and body mass.

METHOD

A randomized, controlled pilot trial was conducted with 29 children, 8 to 13 years who had overweight/obesity and LOC-eating. Youth-parent dyads were randomized to 12-week FB-IPT (n = 15) or FB-HE (n = 14) and evaluated at post-treatment, six-months, and one-year. Changes in child psychosocial functioning, LOC-eating, BMI, and adiposity by dual-energy-X-ray-absorptiometry were assessed. Missing follow-up data were multiply imputed.

RESULTS

FB-IPT feasibility and acceptability were indicated by good attendance (83%) and perceived benefits to social interactions and eating. Follow-up assessments were completed by 73% FB-IPT and 86% FB-HE at post-treatment, 60% and 64% at six-months, and 47% and 57% at one-year. At post-treatment, children in FB-IPT reported greater decreases in depression (95% CI -7.23, -2.01, Cohen's d = 1.23) and anxiety (95% CI -6.08, -0.70, Cohen's d = .79) and less odds of LOC-eating (95% CI -3.93, -0.03, Cohen's d = .38) than FB-HE. At six-months, children in FB-IPT had greater reductions in disordered-eating attitudes (95% CI -0.72, -0.05, Cohen's d = .66) and at one-year, tended to have greater decreases in depressive symptoms (95% CI -8.82, 0.44, Cohen's d = .69) than FB-HE. There was no difference in BMI gain between the groups.

DISCUSSION

Family-based approaches that address interpersonal and emotional underpinnings of LOC-eating in preadolescents with overweight/obesity show preliminary promise, particularly for reducing internalizing symptoms. Whether observed psychological benefits translate into sustained prevention of disordered-eating or excess weight gain requires further study.

© 2017 Wiley Periodicals, Inc.

Address: Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Hatfield Clinical Research Center, Bethesda, Maryland, 20892.; Department of Human Development and Family Studies and the Colorado School of Public Health, Colorado State University, Fort Collins, Colorado, 80523.; Department of Medical and Clinical Psychology, Uniformed Services University of the Health Sciences (USUHS), Bethesda, Maryland, 20814.; Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, North Carolina, 27599.; Department of Preventive Medicine and Biostatistics, USUHS, Bethesda, Maryland, 20814.; Eating Disorder Research Unit, New York State Psychiatric Institute, Columbia University Medical Center, New York, NY, 10032.; Department of Counseling Psychology and Human Services and the Prevention Science Institute, College of Education, University of Oregon, College of Education, University of Oregon, Eugene, Oregon, 97403.; Department of Psychology, University of Pittsburgh at Johnstown, Johnstown, Pennsylvania, 15904.; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, 63110.; Division of Digestive Diseases and Nutrition, National Institute of Diabetes, Digestive, and Kidney Diseases (NIDDK), NIH, Bethesda, Maryland, 20892.
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