ANGPTL3 Inhibition in Homozygous Familial Hypercholesterolemia.

Kuo-Chen Chan, G Kees Hovingh, George D Yancopoulos, Neil Stahl, Jesper Gromada, Viktoria Gusarova, Poulabi Banerjee, Etienne Khoury, Diane Brisson, Daniel Gaudet, William J Sasiela, Kuang-Yuh Chyu, Prediman K Shah, Marina Cuchel, Zahid Ahmad, Robert Pordy, Daniel A Gipe

Journal: The New England journal of medicine 2017;377(3):296-297

PMID: 28723334

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Abstract

Address: Université de Montréal, Chicoutimi, QC, Canada.; Regeneron Pharmaceuticals, Tarrytown, NY.; University of Texas Southwestern Medical Center, Dallas, TX.; Perelman School of Medicine of University of Pennsylvania, Philadelphia, PA.; Cedars-Sinai Heart Institute, Los Angeles, CA.; University of Amsterdam, Amsterdam, the Netherlands.

DOI: 10.1056/NEJMc1705994

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MeSH Terms: Angiopoietin-Like Protein 3, Angiopoietin-like Proteins, Angiopoietins, Antibodies, Monoclonal, Cholesterol, LDL, Genotype, Humans, Hyperlipoproteinemia Type II, Receptors, LDL