Recent advances in vitamins analysis by capillary electrophoresis.

Xu Wang, Kefeng Li, Liping Yao, Chunling Wang, Ann Van Schepdael

Journal: Journal of pharmaceutical and biomedical analysis 2018;147():278-287

PMID: 28784252

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Abstract

Vitamins are essential molecules required for human metabolism such as energy production, immune system and cell formation. Accurate vitamin analysis is critical for disease diagnosis, nutrients assessment, as well as food and drug production. This review gives an overview of the recent developments in the use of capillary electrophoresis combined with different detection techniques for the analysis of vitamins. The period covers mid-2007 until mid-2017. Different separation modes are discussed for the analysis of water-soluble vitamins and fat-soluble vitamins. On-line sample concentration for sensitive analysis is also described. The applications include the analysis of pharmaceutical, dietary supplement and biological samples.

Address: Key Laboratory of Food Nutrition and Safety, Ministry of Education, China College of Food Engineering and Biotechnology, Tianjin University of Science and Technology, Tianjin, 300457, China.; School of Medicine, University of California, San Diego, 92103, CA, United States.; Department of Pharmacy, Xinjiang Production and Construction Corps Hospital, Urumqi, Xinjiang, China.; Pharmaceutical Analysis, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven - University of Leuven, Belgium. Electronic address: [email protected].

DOI: 10.1016/j.jpba.2017.07.030

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MeSH Terms: Electrophoresis, Capillary, Solubility, Vitamins