Conventional Radiology in Crystal Arthritis: Gout, Calcium Pyrophosphate Deposition, and Basic Calcium Phosphate Crystals.

Thibaut Jacques, Paul Michelin, Sammy Badr, Michelangelo Nasuto, Guillaume Lefebvre, Neal Larkman, Anne Cotten

Journal: Radiologic clinics of North America 2017;55(5):967-984

PMID: 28774457

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Abstract

This article reviews the main radiographic features of crystal deposition diseases. Gout is linked to monosodium urate crystals. Classic radiographic features include subcutaneous tophi, large and well-circumscribed paraarticular bone erosions, and exuberant bone hyperostosis. Calcium pyrophosphate deposition (CPPD) can involve numerous structures, such as hyaline cartilages, fibrocartilages, or tendons. CPPD arthropathy involves joints usually spared by osteoarthritis. Basic calcium phosphate deposits are periarticular or intraarticular. Periarticular calcifications are amorphous, dense, and round or oval with well-limited borders, and most are asymptomatic. When resorbing, they become cloudy and less dense with an ill-defined shape and can migrate into adjacent structures.

Address: Division of Radiology and Musculoskeletal Imaging, University Hospital of Lille, Rue du Professeur Emile Laine, Lille Cedex 59037, France; University of Lille, 42, rue Paul Duez, Lille 59000, France. Electronic address: [email protected].; Department of Radiology, CHRU de Rouen, 1 rue de Germont, Rouen Cedex 76031, France.; Division of Radiology and Musculoskeletal Imaging, University Hospital of Lille, Rue du Professeur Emile Laine, Lille Cedex 59037, France; University of Lille, 42, rue Paul Duez, Lille 59000, France.; Department of Radiology, University of Foggia, Viale Luigi Pinto 1, Foggia 71100, Italy.; Department of Radiology, Leeds Teaching Hospital Trust, Chapeltown Road, Leeds, West Yorkshire LS7 4SA, UK.

DOI: 10.1016/j.rcl.2017.04.004

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MeSH Terms: Calcium Phosphates, Calcium Pyrophosphate, Crystal Arthropathies, Gout, Humans, Radiology