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Inflammatory biomarkers of coronary heart disease.

Hongyu Li, Kai Sun, Ruiping Zhao, Jiang Hu, Zhiru Hao, Fei Wang, Yaojun Lu, Fu Liu, Yong Zhang

Journal: Frontiers in bioscience (Landmark edition) 2018;22(3):504-515

PMID: 27814628

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Abstract

Coronary heart disease (CHD), characterized by inflammation and accumulation of plaques mainly comprised of lipids, calcium and inflammatory cells in the walls of coronary arteries. CHD is exacerbated by specific cardiovascular risk factors, such as obesity, diabetes mellitus, and hypertension. The current review focuses on the critical role of traditional inflammatory biomarkers, including interleukin-6, C-reactive protein (CRP), complement, CD40 and myeloperoxidase (MPO), in the pathogenesis of CHD.

Address: Department of Cardiology, Baotou Central Hospital, Baotou, China.; Department of Radiology,Baotou Central Hospital, Baotou, China.; Department of Cardiology, Baotou Central Hospital, Baotou, China, ruiping_zhao@yahoo. com.; Department of Surgery, Baotou Central Hospital, Baotou, China.
DOI: 10.2741/4498

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MeSH Terms: Biomarkers, C-Reactive Protein, CD40 Antigens, CD40 Ligand, Complement System Proteins, Coronary Artery Disease, Coronary Disease, Humans, Inflammation Mediators, Models, Cardiovascular, Peroxidase, Receptors, Interleukin-6, Serum Amyloid A Protein
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