Comparative Effectiveness of Surgical Treatments for Small Renal Masses.

Shree Agrawal, Hillary Sedlacek, Simon P Kim

Journal: The Urologic clinics of North America 2017;44(2):257-267

PMID: 28411917

Full Text on Elsevier Science View on PubMed

Abstract

In the management of small renal masses (SRMs), treatment options include partial nephrectomy (PN), radical nephrectomy (RN), ablation, renal biopsy, and active surveillance. Large series retrospective and meta-analyses demonstrate PN may confer greater preservation of renal function, overall survival, and equivalent cancer control when compared with RN. As newer therapies emerge, we should critically evaluate the risks and benefits associated with the surgical management of SRMs among patients with competing comorbidities, complex tumors, and high-risk disease. Among younger patients with SRMs amenable to resection, optimization of postoperative patient health should be prioritized.

Address: Department of Urology, Case Western Reserve University School of Medicine, 11100 Euclid Avenue, Cleveland, OH 44106, USA.; Department of Urology, Case Western Reserve University School of Medicine, 11100 Euclid Avenue, Cleveland, OH 44106, USA; Center of Health Outcomes and Quality, Urology Institute, University Hospitals Cleveland Medical Center, 11100 Euclid Avenue, Cleveland, OH 44106, USA; Seidman Cancer Center, Cleveland, OH, USA; Cancer Outcomes and Public Policy Effectiveness Research (COPPER) Center, Yale University, New Haven, CT, USA. Electronic address: [email protected].

DOI: 10.1016/j.ucl.2016.12.011