Pulmonary Vasodilators and Anesthesia Considerations.

Jeremy B Green, Brendon Hart, Elyse M Cornett, Alan D Kaye, Ali Salehi, Charles J Fox

Journal: Anesthesiology clinics 2017;35(2):221-232

PMID: 28526144

Full Text on Elsevier Science View on PubMed

Abstract

Pulmonary hypertension (PH) is a complex disease process of the pulmonary vasculature system characterized by elevated pulmonary arterial pressures. Patients with PH are at increased risk for morbidity and mortality, including intraoperatively and postoperatively. Appreciation by the clinical anesthesiologist of the pathophysiology of PH is warranted. Careful and meticulous strategy using appropriate anesthetic medications, pulmonary vasodilator and inotropic agents, and careful fluid management all increase the likelihood of the best possible outcome in this challenging patient population.

Address: Department of Anesthesiology, Louisiana State University Health Science Center-New Orleans, New Orleans, LA, USA.; Department of Anesthesiology, Louisiana State University Health Science Center-Shreveport, Shreveport, LA, USA.; Department of Anesthesiology, Louisiana State University Health Science Center-New Orleans, 1542 Tulane Avenue, New Orleans, LA 70112, USA. Electronic address: [email protected].; Department of Anesthesiology, Ronald Regan UCLA Medical Center, Los Angeles, CA, USA.

DOI: 10.1016/j.anclin.2017.01.008

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MeSH Terms: Anesthesia, Humans, Hypertension, Pulmonary, Muscle, Smooth, Vascular, Nitric Oxide, Pulmonary Circulation, Vascular Resistance, Vasodilator Agents