Vitamin D receptor expression and hepcidin levels in the protection or severity of leprosy: a systematic review.

Ana Laura Grossi de Oliveira, Ana Thereza Chaves, Cristiane Alves Silva Menezes, Nathalia Sernizon Guimarães, Lilian Lacerda Bueno, Ricardo Toshio Fujiwara, Manoel Otávio da Costa Rocha

Journal: Microbes and infection 2018;19(6):311-322

PMID: 28323068

Free Full Text on Elsevier Science View on PubMed

Abstract

Leprosy is a chronic infectious disease whose disequilibrium in the host's genetic, immunological and clinical mechanisms leads to distinct manifestations defining the type of immunological response. This review focuses its attention on the influence of the Vitamin D Receptor and hepcidin expressions that can suggest the protection or severity of leprosy.

Address: Post-graduate Program in Health Sciences: Infectious Diseases and Tropical Medicine, School of Medicine, Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil. Electronic address: [email protected].; Post-graduate Program in Health Sciences: Infectious Diseases and Tropical Medicine, School of Medicine, Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.; Department of Clinical and Toxicological Analyses, School of Pharmacy, UFMG, Brazil.; Department of Parasitology, Institute of Biological Sciences, UFMG, Brazil.

DOI: 10.1016/j.micinf.2017.03.001

Link outs

Free resources

Full Text Sources:

https://linkinghub.elsevier.com/retrieve/pii/S1286...

Medical:

https://medlineplus.gov/mycobacterialinfections.ht...

Other Literature Sources:

https://scite.ai/reports/28323068

MeSH Terms: Databases, Factual, Genetic Predisposition to Disease, Hepcidins, Humans, Leprosy, Polymorphism, Single Nucleotide, Receptors, Calcitriol