Clinical applications of research on fatigue in children with cancer.

Fatigue is a prevalent problem in the pediatric oncology population but is probably under-recognized and undertreated. The research on fatigue in children with cancer presented in this issue offers a welcome exploration of the subject. Clinical nurses must begin to understand the causes and symptoms of fatigue, as well as supportive care measures for their patients. Fatigue can occur in children who receive chemotherapy, radiotherapy, and biotherapy, and in children who are treated with bone marrow transplantation. Education of the patient and family regarding the potential for fatigue is helpful in preparing them for the cancer experience. Factors that contribute to and alleviate fatigue can be identified for each patient, taking into consideration age, developmental level, and cultural background. Parents and patients, especially adolescent patients, may have differing opinions about what fatigue is and what may be helpful. Further research into fatigue in children with cancer is encouraged, especially in patients suffering from alterations in sleep or nutritional status, and in long-term survivors of childhood cancer.