Nacre-inspired nanocomposites produced using layer-by-layer assembly: Design strategies and biomedical applications.

José R Rodrigues, Natália M Alves, João F Mano

Journal: Materials science & engineering. C, Materials for biological applications 2018;76():1263-1273

PMID: 28482494

Full Text on Elsevier Science View on PubMed

Abstract

Biomimetics constitutes an attractive strategy for the development of new functional materials in a variety of fields. Nacre is a natural composite composed of 95% aragonite and 5% organic materials with a layered and hierarchical structure which has be shown to have high toughness and mechanical strength and resistance. As such, mimicking nacre's composition and structure can be the key for the development of new materials with increased mechanical properties and stability. This review focuses on recent developments achieved in the production of nacre-like nanocomposites using the layer-by-layer deposition technique. This technique was chosen due to its ability to create nanostructured layered structures with thickness controlled at the nanoscale level using a wide range of different materials. Several examples of nacre-inspired designs of multilayer nanocomposites are overviewed, and their possible applications are discussed, in particular in the biomedical field.

Address: 3B's Research Group, Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark-Parque de Ciência e Tecnologia, Barco, 4805-017 Guimarães, Portugal; ICVS/3B's, Associate PT Government Laboratory, Braga, Guimarães, Portugal.; 3B's Research Group, Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark-Parque de Ciência e Tecnologia, Barco, 4805-017 Guimarães, Portugal; ICVS/3B's, Associate PT Government Laboratory, Braga, Guimarães, Portugal. Electronic address: [email protected].; 3B's Research Group, Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark-Parque de Ciência e Tecnologia, Barco, 4805-017 Guimarães, Portugal; ICVS/3B's, Associate PT Government Laboratory, Braga, Guimarães, Portugal. Electronic address: [email protected].

DOI: 10.1016/j.msec.2017.02.043

Link outs

Free resources

Other Literature Sources:

https://scite.ai/reports/28482494

Research Materials:

https://antibodies.cancer.gov/detail/CPTC-HLA-B-1

Subscription / membership required

Full Text Sources:

https://linkinghub.elsevier.com/retrieve/pii/S0928...

MeSH Terms: Biomimetic Materials, Biomimetics, Calcium Carbonate, Nacre, Nanocomposites