Nutrition and neurodevelopmental outcomes in preterm infants: a systematic review.

Stephanie H T Chan, Mark J Johnson, Alison A Leaf, Brigitte Vollmer

Journal: Acta paediatrica (Oslo, Norway : 1992) 2017;105(6):587-99

PMID: 26813585

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Abstract

UNLABELLED

A systematic review with meta-analysis was carried out to investigate the effects of increased nutritional intake, via either macronutrient or multinutrient intervention, during the neonatal period on neurodevelopmental outcomes in infants born at <32 weeks of gestation or weighing <1501 g at birth.

CONCLUSION

Although the relationship remains unclear, increased early nutrition may reduce neurodevelopmental impairment in this group of infants. Future research should focus on using standardised nutritional interventions and an agreed neurodevelopmental assessment battery.

Address: Faculty of Medicine, University of Southampton, Southampton, UK.; NIHR Biomedical Research Centre Southampton, University Hospital Southampton NHS Foundation Trust and University of Southampton, Southampton, UK.; Department of Neonatal Medicine, Southampton Children's Hospital, University Hospital Southampton NHS Foundation Trust, Southampton, UK.; Clinical and Experimental Sciences, Clinical Neurosciences, Faculty of Medicine, University of Southampton, Southampton, UK.; Neonatal and Paediatric Neurology, Southampton Children's Hospital, University Hospital Southampton NHS Foundation Trust, Southampton, UK.

DOI: 10.1111/apa.13344

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MeSH Terms: Humans, Infant Nutritional Physiological Phenomena, Infant, Newborn, Infant, Premature, Infant, Very Low Birth Weight, Neurodevelopmental Disorders