Parity and serum lipid levels: a cross-sectional study in chinese female adults.

Haichen Lv, Xiaolei Yang, Yong Zhou, Jing Wu, Henghui Liu, Youxin Wang, Yuanming Pan, Yunlong Xia

Journal: Scientific reports 2018;6():33831

PMID: 27645134

Abstract

Reproductive factors have been shown to correlate with lipid metabolism. The aim of this study was to investigate the relationship between parity and serum lipid levels in community-based Chinese female adults. A total of 4,217 female participants were enrolled. Parity was recorded according to questionnaire and serum lipid profile, including triglycerides (TG), total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), and high density lipoprotein cholesterol (HDL-C), was measured. Logistic regression models were used to analyze the association of parity to serum lipid levels, while adjusting for demographics and metabolic risk factors. Parity in this population ranged from 0 to 7. After adjusting for potential confounders, it indicated that females with more than 2 parities appeared to be less likely to suffer from abnormal serum TC level compared with nulliparae (parity = 2, odds ratio (OR) = 0.457, 95% confidence interval (CI) = 0.284-0.736; parity ≥ 3, OR = 0.363, 95% CI = 0.202-0.653). These findings suggested that parity could correlate with lipid metabolism in Chinese women. Individuals with higher parity appeared to have a lower total cholesterol in blood.

Address: Department of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, China.; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; School of Public Health, Dalian Medical University, Dalian, China.; Beijing Recdata Technology Co. Ltd., Beijing, China.; Beijing Municipal Key Laboratory of Clinical Epidemiology, School of Public Health, Capital Medical University, Beijing, China.
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