Detection of cardiovascular calcifications: Is it a useful tool for nephrologists?

Jordi Bover, José Luis Górriz, Pablo Ureña-Torres, María Jesús Lloret, César Ruiz-García, Iara daSilva, Pamela Chang, Mariano Rodríguez, José Ballarín

Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 2018;36(6):587-596

PMID: 27575927

Abstract

Chronic kidney disease (CKD) has been used as a model and source of knowledge concerning the mechanisms, clinical relevance and accelerated progression of cardiovascular (CV) calcification, as well as its consequences in clinical practice, despite we know that it is a late secondary ossification phenomenon and only circumstantial evidence is available. In this comprehensive review, we firstly describe the types of CV calcification which affect CKD patients, and we analyse how its presence is directly associated with CV events and increased mortality in these patients. We also justify the use of CV calcification assessment in regular nephrology clinical practice, because CV calcification is an important predictor of clinical outcome in these patients. Consequently, we believe that CV calcification assessment is a tool that could and should be used by nephrologists when making a decision concerning individual patients, consistent with the current trend of an ever-more-personalised therapeutic approach.

Copyright © 2016 Sociedad Española de Nefrología. Published by Elsevier España, S.L.U. All rights reserved.

Address: Servicio de Nefrología, Fundació Puigvert, IIB Sant Pau, RedinRen, Barcelona, España. Electronic address: [email protected].; Servicio de Nefrología, Hospital Universitario Doctor Peset, Valencia, España.; Departamento de Nefrología y Diálisis, Clinique du Landy, Departamento de Fisiología Renal, Hospital Necker, Universidad de París Descartes, París, Francia.; Servicio de Nefrología, Fundació Puigvert, IIB Sant Pau, RedinRen, Barcelona, España.; Servicio de Nefrología, Hospital de Universitario Reina Sofía, IMIBIC, Universidad de Córdoba, Córdoba, España.
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