Comparison of the PEEK cage and an autologous cage made from the lumbar spinous process and laminae in posterior lumbar interbody fusion.

Bin Lin, Hui Yu, Zhida Chen, Zhuanzhi Huang, Wenbin Zhang

Journal: BMC musculoskeletal disorders 2017;17(1):374

PMID: 27577978

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Abstract

BACKGROUND

A prospective cohort study was performed to evaluate the clinical and radiological outcomes following posterior lumbar interbody fusion (PLIF) in patients treated with a PEEK cage compared to those treated with an autologous cage using the lumbar spinous process and laminae (ACSP).

METHODS

Sixty-nine consecutive patients with lumbar degenerative disc disease were randomly assigned to either a PEEK cage (group A, n = 34) or an ACSP (group B, n = 35). Monosegmental PLIF was performed in all patients. Mean lumbar lordosis, mean disc height, visual analog scale (VAS) scores, functional outcomes, fusion rates and complication rates were recorded and compared. The patients were followed postoperatively for a minimum of 2 years.

RESULTS

Successful radiographic fusion was documented in all patients. No flexion-extension hypermobility or pedicle screw loosening or breakage occurred during the follow-up period. No significant difference existed between the 2 groups when comparing the mean lumbar lordosis, mean disc height, visual analog scale (VAS) scores, functional outcomes, fusion rates or complication rates. Overall satisfactory results were achieved in both groups.

CONCLUSIONS

The results suggest that the ACSP appears to be equally as safe and effective as the PEEK cage.

TRIAL REGISTRATION

ISRCTN25558534 . Retrospectively registered 16/02/2016.

Address: Department of Orthopaedics, the 175th Hospital of PLA, Southeast Hospital of Xiamen University, 269 Zhanghua Road, Zhangzhou, Fujian, 363000, People's Republic of China. [email protected].; Department of Orthopaedics, the 175th Hospital of PLA, Southeast Hospital of Xiamen University, 269 Zhanghua Road, Zhangzhou, Fujian, 363000, People's Republic of China.

DOI: 10.1186/s12891-016-1237-y

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MeSH Terms: Adult, Benzophenones, Biocompatible Materials, Bone Transplantation, Female, Follow-Up Studies, Humans, Intervertebral Disc Degeneration, Ketones, Lordosis, Lumbar Vertebrae, Lumbosacral Region, Magnetic Resonance Imaging, Male, Middle Aged, Pain Measurement, Pedicle Screws, Polyethylene Glycols, Polymers, Prospective Studies, Radiography, Spinal Fusion, Tomography, X-Ray Computed, Transplantation, Autologous, Treatment Outcome