Neurologic Manifestations of Blood Dyscrasias.

Daniel R Couriel, Holly Ricker, Mary Steinbach, Catherine J Lee

Journal: Hematology/oncology clinics of North America 2017;30(4):723-31

PMID: 27443994

Full Text on Elsevier Science View on PubMed

Abstract

Neurologic manifestations are common in blood diseases, and they can be caused by the hematologic disorder or its treatment. This article discusses hematologic diseases in adult patients, and categorizes them into benign and malignant conditions. The more common benign hematologic diseases associated with neurologic manifestations include anemias, particularly caused by B12 deficiency and sickle cell disease, and a variety of disorders of hemostasis causing bleeding or thrombosis, including thrombotic microangiopathy. Malignant conditions like multiple myeloma, leukemias, and lymphomas can have neurologic complications resulting from direct involvement, or caused by the different therapies to treat these cancers.

Address: Blood and Marrow Transplantation Program, Huntsman Cancer Institute, University of Utah, 2000 Circle of Hope, Salt Lake City, UT 84112, USA. Electronic address: [email protected].; Blood and Marrow Transplantation Program, Huntsman Cancer Institute, University of Utah, 2000 Circle of Hope, Salt Lake City, UT 84112, USA.

DOI: 10.1016/j.hoc.2016.03.001

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MeSH Terms: Adult, Anemia, Sickle Cell, Humans, Leukemia, Lymphoma, Multiple Myeloma, Nervous System Diseases, Thrombotic Microangiopathies, Vitamin B 12 Deficiency