Endocrine Disorders in Cystic Fibrosis.

Scott M Blackman, Vin Tangpricha

Journal: Pediatric clinics of North America 2017;63(4):699-708

PMID: 27469183

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Abstract

Cystic fibrosis is frequently complicated by endocrine disorders. Diabetes can be expected to affect most with CF and pancreatic insufficiency and varies widely in age of onset, but early identification and treatment improve morbidity and mortality. Short stature can be exacerbated by relative delay of puberty and by use of inhaled corticosteroids. Bone disease in CF causes fragility fractures and should be assessed by monitoring bone mineral density and optimizing vitamin D status. Detecting and managing endocrine complications in CF can reduce morbidity and mortality in CF. These complications can be expected to become more common as the CF population ages.

Address: Division of Pediatric Endocrinology, Department of Pediatrics, Johns Hopkins Hospital, Johns Hopkins University, 200 North Wolfe Street, Baltimore, MD 21287, USA. Electronic address: [email protected].; Division of Endocrinology, Metabolism and Lipids, Department of Medicine, Atlanta VA Medical Center, Emory University School of Medicine, 101 Woodruff Circle NE, WMRB1301, Atlanta, GA 30322, USA.

DOI: 10.1016/j.pcl.2016.04.009

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MeSH Terms: Cystic Fibrosis, Endocrine System Diseases, Female, Humans, Male