A GWAS meta-analysis suggests roles for xenobiotic metabolism and ion channel activity in the biology of stool frequency.

Soesma A Jankipersadsing, Fatemeh Hadizadeh, Marc Jan Bonder, Ettje F Tigchelaar, Patrick Deelen, Jingyuan Fu, Anna Andreasson, Lars Agreus, Susanna Walter, Cisca Wijmenga, Pirro Hysi, Mauro D'Amato, Alexandra Zhernakova

Journal: Gut 2018;66(4):756-758

PMID: 27473416

Abstract

Address: Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden.; School of Nutrition, Isfahan University of Medical Sciences, Isfahan, Iran.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Top Institute Food and Nutrition, Wageningen, The Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; University of Groningen, University Medical Center Groningen, Genomics Coordination Center, Groningen, The Netherlands.; Division of Family Medicine, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.; Stress Research Institute, Stockholm University, Stockholm, Sweden.; Division of Family Medicine, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.; Division of Gastroenterology, Institution of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.; Department of Ophthalmology, King's College London, St Thomas' Hospital Campus, London, UK.; Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden.; BioDonostia Health Research Institute San Sebastian and IKERBASQUE, Basque Foundation for Science, Bilbao, Spain.
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