Anne C R Tanner, Christine A Kressirer, Lina L Faller
Journal: Journal of the California Dental Association 2016;44(7):437-46
PMID: 27514155
Dental caries is a major disease of the oral cavity with profound clinical significance. Caries results from a transition of a healthy oral microbiome into an acidogenic community of decreased microbial diversity in response to excessive dietary sugar intake. Microbiological cultivation, molecular identification, gene expression and metabolomic analyses show the importance of the entire microbial community in understanding the role of the microbiome in the pathology of caries.
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