The use of a biocompatible cement in endodontic surgery. A randomized clinical trial 1.

Sérgio Ribeiro da Silva, José Dias da Silva, Taylor Brandão Schnaider, Daniela Francescato Veiga, Neil Ferreira Novo, Marcos Mesquita, Lydia Masako Ferreira

Journal: Acta cirurgica brasileira 2017;31(6):422-7

PMID: 27355751

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Abstract

PURPOSE

To evaluate the clinical applicability of Pozzolana Biologic Silva cement (PBS(r)) in endodontic surgery.

METHODS

Persistent apical periodontitis was diagnosed in 30 teeth of 12 patients by cone-beam computed tomography (CT). All patients had 2 or 4 affected teeth and underwent endodontic surgery with root-end filling. Patients with 2 affected teeth had one tooth (control) treated with mineral trioxide aggregate (MTA-Angelus(r)) as a root-end filling material, and the other tooth treated with PBS (experiment). When the patient had four affected teeth, two of them were treated with MTA and two with PBS. Six months after surgery, all patients were assessed by CT scan. Between-group comparisons of measurements were performed using the Wilcoxon test.

RESULTS

Periradicular tissue regeneration was observed in all cases. Significant within-group differences in long axes of the lesion were found in the bucco-palatal direction (PBS group, p=0.0012; MTA group, p=0.024) and coronal-apical direction (PBS group, p=0.0007; MTA group, p=0.0015) between pre- and postoperative measurements.

CONCLUSIONS

Pozzolana Biologic Silva cement can be used in the treatment of persistent periradicular lesions. The clinical use of PBS as a root-end filling material may be an alternative to MTA. PBS has additives, which provide enhanced strength.

Address: Fellow Master degree, Professional Master's Program in Applied Health, Universidade di Vale do Sapucaí (UNIVÁS), Pouso Alegre-MG, and Universidade Federal de São Paulo (UNIFESP), Sao Paulo-SP, Brazil. Conception, design, intellectual and scientific content of the study; acquisition, interpretation and analysis of data; manuscript writing.; PhD, Associate Professor, Professional Master's Program in Applied Health Sciences, UNIVÁS, Pouso Alegre-MG, Brazil. Conception, design, intellectual and scientific content of the study; acquisition, interpretation and analysis of data; manuscript writing; critical revision.; PhD, Full Professor, Department of Surgery, UNIVÁS, Pouso Alegre-MG, Brazil. Conception, design, intellectual and scientific content of the study; interpretation and analysis of data; critical revision.; PhD, Full Professor, Department of Surgery, UNIFESP, Sao Paulo-SP, and UNIVÁS, Pouso Alegre-MG, Brazil. Interpretation and analysis of data, critical revision.; PhD, Department of Biostatistics, UNIVÁS, Pouso Alegre-MG, Brazil. Statistical analysis.; PhD, Full Professor, Department of Biostatistics, UNIVÁS, Pouso Alegre-MG, Brazil. Interpretation of data, statistical analysis, critical revision.; PhD, Full Professor, Department of Surgery, UNIFESP, Sao Paulo-SP, Brazil. Interpretation and analysis of data, critical revision.

DOI: 10.1590/S0102-865020160060000010

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MeSH Terms: Adolescent, Adult, Aluminum Compounds, Apicoectomy, Biocompatible Materials, Calcium Compounds, Cone-Beam Computed Tomography, Dental Cements, Drug Combinations, Humans, Middle Aged, Oxides, Periapical Periodontitis, Postoperative Period, Prospective Studies, Regeneration, Root Canal Filling Materials, Silicates, Tooth Root, Young Adult