Severe rhabdomyolysis secondary to adenovirus infection: case report and literature review.

Daniel Tseytlin, Sharon Maynard

Journal: Clinical nephrology 2016;85(4):245-50

PMID: 26857631

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Abstract

A 38-year-old male presented with renal failure in the setting of a flu-like illness. Urinalysis showed myoglobinuria and granular casts. His serum creatine phosphokinase was markedly elevated. He was diagnosed with rhabdomyolysis and was volume resuscitated with normal saline and bicarbonate-containing fluid. Workup included a respiratory viral panel which was positive for adenovirus. Other causes such as trauma, seizure, and intoxicants were excluded. He developed progressive renal failure necessitating hemodialysis. After ~ 4 weeks he recovered renal function and dialysis was discontinued. Viral-induced myopathy should be suspected in patients who present with rhabdomyolysis.

DOI: 10.5414/CN108649

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MeSH Terms: Adenovirus Infections, Human, Adult, Creatine Kinase, Fluid Therapy, Humans, Hyperkalemia, Hyperphosphatemia, Hypocalcemia, Male, Myoglobinuria, Renal Dialysis, Renal Insufficiency, Respiratory Tract Infections, Rhabdomyolysis