Response of metastatic epidermoid anal cancer to single agent irinotecan: a case report.

F Grifaichi, A Padovani, F Romeo, C Trinca, L Moscetti, E Cortesi

Journal: Tumori 2002;87(1):58-9

PMID: 11669560

Abstract

We report a case of a patient affected by epidermoid anal cancer who had hepatic progression after standard therapy with the Nigro regimen (fluorouracil and mitomycin C plus radiotherapy). This is an uncommon neoplasm against which only few chemotherapeutic agents have been tested. In our patient salvage treatment with low dose irinotecan resulted in a partial response.

Address: Department of Experimental Medicine, University La Sapienza, Policlinico Umberto I, Rome, Italy.

DOI: 10.1177/030089160108700113

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MeSH Terms: Antineoplastic Agents, Phytogenic, Anus Neoplasms, Camptothecin, Carcinoma, Squamous Cell, Female, Humans, Irinotecan, Middle Aged, Treatment Outcome