Are pharmacological randomised controlled clinical trials relevant to real-life asthma populations? A protocol for an UNLOCK study from the IPCRG.

Address: Department of Public Health and Caring Science, Family Medicine and Preventive Medicine, Uppsala University, Uppsala, Sweden.; ICVS/3B's - PT Government Associate Laboratory, Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal.; Department of Primary and Community Care, Radboud University Nijmegen, Nijmegen, The Netherlands.; Department of General Practice, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; GRIAC Research Institute Groningen, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Academic Primary Care, Division of Applied Health Sciences, University of Aberdeen, Aberdeen, UK.; Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands.