A survey of synthetic nicotinamide cofactors in enzymatic processes.

Caroline E Paul, Frank Hollmann

Journal: Applied microbiology and biotechnology 2017;100(11):4773-8

PMID: 27094184

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Abstract

Synthetic nicotinamide cofactors are analogues of the natural cofactors used by oxidoreductases as redox intermediates. Their ability to be fine-tuned makes these biomimetics an attractive alternative to the natural cofactors in terms of stability, reactivity, and cost. The following mini-review focuses on the current state of the art of those biomimetics in enzymatic processes.

Address: Department of Biotechnology, Delft University of Technology, Julianalaan 136, 2628BL, Delft, The Netherlands. [email protected].; Department of Biotechnology, Delft University of Technology, Julianalaan 136, 2628BL, Delft, The Netherlands.

DOI: 10.1007/s00253-016-7500-1

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MeSH Terms: Biomimetic Materials, Biomimetics, Dinitrocresols, Niacinamide, Oxidation-Reduction, Oxidoreductases