Mechanisms Linking the Gut Microbiome and Glucose Metabolism.

Kristina M Utzschneider, Mario Kratz, Chris J Damman, Meredith Hullar

Journal: The Journal of clinical endocrinology and metabolism 2017;101(4):1445-54

PMID: 26938201

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Abstract

This review details potential mechanisms linking gut dysbiosis to metabolic dysfunction, including lipopolysaccharide, bile acids, short chain fatty acids, gut hormones, and branched-chain amino acids.

Address: Division of Metabolism, Endocrinology and Nutrition (K.M.U.), Department of Medicine, VA Puget Sound Health Care System and the University of Washington, Seattle, Washington; Division of Public Health Sciences (M.K.), Fred Hutchinson Cancer Research Center, and the Department of Epidemiology, University of Washington, Seattle, Washington; Division of Gastroenterology (C.J.D.), Department of Medicine, University of Washington, Seattle, Washington; and Division of Public Health Sciences (M.H.), Fred Hutchinson Cancer Research Center, Seattle, Washington.

DOI: 10.1210/jc.2015-4251

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MeSH Terms: Dysbiosis, Gastrointestinal Microbiome, Glucose, Humans