Introduction: The Complexity and Challenge of Preventing, Treating, and Managing Blood Diseases in the Developing Countries.

David J Roberts, David J Weatherall

Journal: Hematology/oncology clinics of North America 2016;30(2):233-46

PMID: 27040954

Full Text on Elsevier Science View on PubMed

Abstract

Managing hematologic disorders in developing countries poses problems not encountered in Western societies. The clinical features of hematologic conditions may be modified by malnutrition, chronic bacterial infection, or parasitic illness. Iron deficiency is the major factor in anemia worldwide. Anemia is more common in the wet season when malaria transmission peaks. After anemia, eosinophilia is the next most common hematologic abnormality in children in the tropics. Infection with the human immunodeficiency virus can cause hematologic abnormalities. The pattern of distribution of primary disorders of the blood varies among populations and some disorders are unique to certain parts of the world.

Address: Radcliffe Department of Medicine, University of Oxford and National Health Service Blood and Transplant, John Radcliffe Hospital, Level 2, Oxford OX3 9DS, UK. Electronic address: [email protected].; Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, UK.

DOI: 10.1016/j.hoc.2015.11.001

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MeSH Terms: Age Factors, Anemia, Comorbidity, Developing Countries, Disease Management, Eosinophilia, HIV Infections, Hematologic Diseases, Hemostatic Disorders, Humans, Malabsorption Syndromes, Prevalence