Stress Hyperglycemia During Surgery and Anesthesia: Pathogenesis and Clinical Implications.

Nadine E Palermo, Roma Y Gianchandani, Marie E McDonnell, Sara M Alexanian

Journal: Current diabetes reports 2016;16(3):33

PMID: 26957107

Abstract

Numerous studies have demonstrated an association between hyperglycemia in the perioperative period and adverse clinical outcomes. Many patients who experience hyperglycemia while hospitalized do not have a known history of diabetes and experience a transient phenomenon often described as "stress hyperglycemia" (SH). We discuss the epidemiology and pathogenesis of SH as well as evidence to date regarding predisposing factors and outcomes. Further research is needed to identify the long-term sequelae of SH as well as perioperative measures that may modulate glucose elevations and optimal treatment strategies.

Address: Department of Medicine, Division of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Ave, Suite 381, Boston, MA, 02115, USA. [email protected].; Department of Medicine, Division of Metabolism, Endocrinology and Diabetes, University of Michigan Health Systems, University of Michigan Medical School, 24 Frank Lloyd Wright Drive, Ann Arbor, MI, 48109, USA. [email protected].; Department of Medicine, Division of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Ave, Suite 381, Boston, MA, 02115, USA. [email protected].; Department of Medicine, Section of Endocrinology, Diabetes and Nutrition, Boston Medical Center, Boston University School of Medicine, 732 Harrison Ave, 5th Floor, Suite 511, Boston, MA, 02118, USA. [email protected].

DOI: 10.1007/s11892-016-0721-y

Link outs

Free resources

Medical:

Other Literature Sources:

https://scite.ai/reports/26957107

Subscription / membership required

Full Text Sources:

https://dx.doi.org/10.1007/s11892-016-0721-y

MeSH Terms: Anesthesia, Blood Glucose, Humans, Hyperglycemia, Perioperative Care, Perioperative Period, Stress, Physiological