Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma.

Address: Department of Epidemiology and Biostatistics, Institute for Computational Biology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.; Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA.; Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Department of Ophthalmology, Duke University Medical Center, Durham, North Carolina, USA.; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; Division of Human Genetics, Genome Institute of Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia.; Department of Ophthalmology, Flinders University, Adelaide, South Australia, Australia.; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.; Division of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.; Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.; Center for Human Genetics, Marshfield Clinic Research Foundation, Marshfield, Wisconsin, USA.; Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland.; Department of Ophthalmology, University of North Carolina, Chapel Hill, North Carolina, USA.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Eye Academic Clinical Program, Duke-National University of Singapore Graduate Medical School, Singapore.; Section of Rheumatology and Clinical Epidemiology Unit, Boston University School of Medicine, Boston, Massachusetts, USA.; Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Renal Division, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.; Department of Ophthalmology, University of Iowa, College of Medicine, Iowa City, Iowa, USA.; Department of Anatomy and Cell Biology, University of Iowa, College of Medicine, Iowa City, Iowa, USA.; National Institute for Health Research Biomedical Research Centre at Moorfields Eye Hospital, London, UK.; Department of Ophthalmology, University College London, London, UK.; Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.; Eye Doctors of Washington, Chevy Chase, Maryland, USA.; Scripps Genome Center, University of California at San Diego, San Diego, California, USA.; Centre for Eye Research Australia, University of Melbourne, Melbourne, Victoria, Australia.; Department of Ophthalmology, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia.; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA.; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.; Program in Genetic Epidemiology and Statistical Genetics, Harvard School of Public Health, Boston, Massachusetts, USA.; Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge School of Clinical Medicine, Cambridge, UK.; Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA.; Division of Human Genetics, Genome Institute of Singapore, Singapore.; Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, Michigan, USA.; Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia.; Centre for Ophthalmology and Visual Science, Lions Eye Institute, University of Western Australia, Perth, Western Australia, Australia.; Medical Research Council Social Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, King's College London, London, UK.; Centre for Vision Research, Westmead Millennium Institute, University of Sydney, Westmead, New South Wales, Australia.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Duke-National University of Singapore Graduate Medical School, Singapore.; The Jackson Laboratory, Bar Harbor, Maine, USA.; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, USA.; Department of Ophthalmology, West Virginia University Eye Institute, Morgantown, West Virginia, USA.; Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, Michigan, USA.; Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA.; Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA.; Einhorn Clinical Research Center, Department of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, New York, USA.; Center for Systems Genomics, Pennsylvania State University, University Park, Pennsylvania, USA.; Department of Ophthalmology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, Florida, USA.; Department of Ophthalmology, Stanford University School of Medicine, Palo Alto, California, USA.; Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, USA.; Department of Ophthalmology, School of Medicine, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece.; National Institute for Health Research Biomedical Research Centre at Moorfields Eye Hospital, London, UK.; Department of Genetics, Stanford University School of Medicine, Palo Alto, California, USA.; Institute for Ophthalmic Research, Centre for Ophthalmology, University of Tübingen, Tübingen, Germany.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Genentech, San Francisco, California, USA.; Wilmer Eye Institute, Johns Hopkins University Hospital, Baltimore, Maryland, USA.; Hamilton Glaucoma Center, Shiley Eye Institute, University of California, San Diego, San Diego, California, USA.; Department of Cellular Biology and Anatomy, Georgia Regents University, Augusta, Georgia, USA.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Eye Academic Clinical Program, Duke-National University of Singapore Graduate Medical School, Singapore.; Department of Cellular Biology and Anatomy, Georgia Regents University, Augusta, Georgia, USA.; James and Jean Culver Vision Discovery Institute, Georgia Regents University, Augusta, Georgia, USA.; Department of Ophthalmology, Flinders University, Adelaide, South Australia, Australia.; Department of Ophthalmology, Duke University Medical Center, Durham, North Carolina, USA.; Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.; Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA.; Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.