Evaluation of the effectiveness of a chamomile (Matricaria chamomilla) and linseed (Linum usitatissimum) saliva substitute in the relief of xerostomia in elders.

Irene Morales-Bozo, Ana Ortega-Pinto, Gonzalo Rojas Alcayaga, Juan P Aitken Saavedra, Olga Salinas Flores, Claudia Lefimil Puente, Carla Lozano Moraga, José M Manríquez Urbina, Blanca Urzúa Orellana

Journal: Gerodontology 2018;34(1):42-48

PMID: 26763612

Abstract

OBJECTIVE

The aim of this study was to determine the efficacy of a chamomile (Matricaria chamomilla) and linseed (Linum usitatissimum) saliva substitute in the relief of xerostomia in older participants.

BACKGROUND

In elders, xerostomia is a permanent and progressive condition that significantly affects their quality of life. The treatment for progressive xerostomia is currently restricted to palliative measures, and saliva substitutes are indicated. A lack of evidence on the effectiveness of the saliva substitutes in the relief of symptoms of xerostomia has been reported.

MATERIALS AND METHODS

Seventy-four elderly participants presenting xerostomia of diverse origin were selected. Herbal saliva substitute and carboxymethyl cellulose conventional saliva substitute were tested using a double-blind, randomised, cross-sectional clinical trial.

RESULTS

Every participant of the study exhibited dry mouth sensation. A sensation of thick saliva was described in 59.5% of the participants. The need for liquid intake to swallow food, the sensation of difficulty in swallowing and the burning sensation in the tongue were observed in 54.1, 56.8 and 27.0% of the participants, respectively. The most prevalent diseases were hypertension, depressive symptoms and arthritis. Results of the clinical tests showed that the herbal saliva substitute produced a greater relief of dry mouth symptoms, thick saliva sensation and the sensation of difficulty in swallowing than the conventional substitute (Wilcoxon test p < 0.05).

CONCLUSIONS

New chamomile- and linseed-based saliva substitute was effective in relieving xerostomia symptoms in older participants of this study.

© 2016 John Wiley & Sons A/S and The Gerodontology Association. Published by John Wiley & Sons Ltd.

Address: Institute for Research in Dental Sciences, Faculty of Dentistry, University of Chile, Santiago, Chile.; Department of Pathology and Oral Medicine, Faculty of Dentistry, University of Chile, Santiago, Chile.; Health Reference Centre of Peñalolén Cordillera Oriente, Santiago, Chile.

Link outs

Bant logo

© Copyright 2026, Nutrition Evidence

NED wishes to thank the following organisations for their support:

We use cookies to improve your experience and analyze site traffic with Google Analytics. By continuing to use our site, you agree to our use of cookies. Learn more.