Medical Functions of Hydrogen Sulfide.

Beata Olas

Journal: Advances in clinical chemistry 2016;74():195-210

PMID: 27117664

Full Text on Elsevier Science View on PubMed

Abstract

Hydrogen sulfide (H(2)S) is a gasomediator synthesized from L- and D-cysteine in various tissues. It is involved in a number of physiological and pathological processes. H(2)S exhibits antiatherosclerotic, vasodilator, and proangiogenic properties, and protects the kidney and heart from damage following ischemia/reperfusion injury. H(2)S donors may be natural or synthetic, and may be used for the safe treatment of a wide range of diseases. This review article summarizes the current state of knowledge of the therapeutic function of H(2)S.

Address: Department of General Biochemistry, Faculty of Biology and Environmental Protection, University of Lodz, Lodz, Poland. Electronic address: [email protected].

DOI: 10.1016/bs.acc.2015.12.007

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MeSH Terms: Angiogenesis Inducing Agents, Cardiovascular Agents, Cysteine, Diclofenac, Disulfides, Heart, Humans, Hydrogen Sulfide, Kidney, Levodopa, Prostaglandins F, Synthetic, Reperfusion Injury, Sulfides, Thioctic Acid, Thiones, Vasodilator Agents