Phaeohyphomycosis Due to Exophiala jeanselmei: An Emerging Pathogen in India--Case Report and Review.

Swati Bhardwaj, Malini R Capoor, Sachin Kolte, Geeta Purohit, Leelavathi Dawson, Kusum Gupta, V Ramesh, Ashish Kumar Mandal

Journal: Mycopathologia 2016;181(3-4):279-84

PMID: 26476655

Abstract

We present a rare case of a 30-year-old woman who presented with a swelling on the lateral aspect of her left forearm, present since 6 months, adjacent to a 16-year-old burn scar. X-ray of elbow joint and forearm revealed the subcutaneous nature of the swelling. Giemsa and periodic acid-Schiff-stained smears and potassium hydroxide mount of fine-needle aspirate of the swelling revealed dematiaceous, branching, and septate fungal hyphae. Fungal culture of the aspirated pus showed growth of Exophiala jeanselmei. Histopathological examination revealed brown-coloured hyphae with foreign body giant cell reaction and palisading granulomas in the surrounding tissue. The patient was successfully treated with surgical excision of the swelling. All the cases of phaeohyphomycosis due to Exophiala spp. in India are also reviewed.

Address: Department of Pathology, VMMC and Safdarjung Hospital, New Delhi, India.; Department of Microbiology, VMMC and Safdarjung Hospital, 203, Naveen Apartments, SainikVihar, Peetampura, New Delhi, India. [email protected].; Department of Microbiology, VMMC and Safdarjung Hospital, 203, Naveen Apartments, SainikVihar, Peetampura, New Delhi, India.; Department of Dermatology, VMMC and Safdarjung Hospital, New Delhi, India.

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